The physical and hormonal alterations induced by pregnancy, childbirth, and the puerperium are associated with numerous cutaneous changes. Some occur so frequently that they are not considered abnormal and vary only in degree. This chapter discusses these physiologic changes, the…
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A. Standard textbooks of dermatopathology 1. Barnhill R.L., Crowson A.N., Magro C.: Barnhill’s dermatopathology.4th edn.2020.McGraw-Hill 2. Busam K.J.Dermatopathology.2016.Saunders 3. Elder D.E., Elenitsas R., Rosenbach M.: Lever’s histopathology of the skin.11th edn.2014.Lippincott-Williams & Wilkins 4. Patterson J.W.: Weedon’s skin pathology.5th edn.2020.Elsevier…
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29.1 Nevus lipomatosus (see Fig. 29.1 ) Rare clustered papules or nodules of the buttock with onset at birth or childhood. ■ Adipose present in superficial dermis ■ Increased dermal blood vessels often Differential diagnosis 1. Lipofibroma variant of acrochordon…
It is beyond the scope of this book to discuss all of the neoplasms that may metastasize to the skin. The more common or characteristic tumors are mentioned below. Breast cancer is the most common malignancy that metastasizes to skin,…
27.1 Dermatofibroma (DF, benign fibrous histiocytoma, subepidermal nodular fibrosis) (see Fig. 27.1A–I ) Brownish (1.18) nodules most common on the legs (1.67), also seen on upper extremities and trunk, rarely on the head or neck, probably originating from folliculitis, arthropod…
26.1 Neurofibroma (NF) (see Fig. 26.1A–D ) Common soft , skin-colored or violaceous papules or nodules (1.129), pedunculated (1.106), or subcutaneous (1.135), may exhibit “buttonhole sign” whereby they can be invaginated with finger compression. ■ Somewhat demarcated nodule in the…
Vascular neoplasms and proliferations in this chapter are mainly made up of endothelial cells that line blood vessels or lymphatics. These cells are generally positive for factor VIII-related antigen, Ulex europaeus lectin, CD31, CD34, FLI-1, and ERG. 25.1 Hemangioma and…
A detailed classification of myeloproliferative disorders is complex and constantly in flux, with continued advances in immunophenotyping, gene rearrangement studies, fluorescence in situ hybridization, microarrays, comparative genomic hybridization, and laser-based microdissection. Indeed, this chapter was without a doubt the worst…