Essential thrombocythemia (ET) is a chronic myeloproliferative neoplasm (MPN) characterized by platelet counts in excess of 450 × 10 9 /L, profound bone marrow (BM) megakaryocyte hyperplasia, leukocytosis, splenomegaly, a clinical course punctuated by hemorrhagic and/ or thrombotic episodes, and…
Under normal conditions, the red blood cell (RBC) mass in humans is tightly controlled and remains relatively constant in a given individual. The numbers of senescent RBCs lost daily are replaced by newly formed ones by a carefully controlled network…
Defining and classifying tumors of the hematopoietic and lymphoid tissue accurately is critical for providing optimal treatment to patients with hematologic malignancies. Explicit definitions and terminologies are prerequisites for the precise classification of hematologic malignancies. A reproducible classification that is…
Essential thrombocythemia (ET) is a chronic myeloproliferative neoplasm (MPN) characterized by platelet counts in excess of 450 × 10 9 /L, profound bone marrow (BM) megakaryocyte hyperplasia, leukocytosis, splenomegaly, a clinical course punctuated by hemorrhagic and/ or thrombotic episodes, and…
Under normal conditions, the red blood cell (RBC) mass in humans is tightly controlled and remains relatively constant in a given individual. The numbers of senescent RBCs lost daily are replaced by newly formed ones by a carefully controlled network…
Defining and classifying tumors of the hematopoietic and lymphoid tissue accurately is critical for providing optimal treatment to patients with hematologic malignancies. Explicit definitions and terminologies are prerequisites for the precise classification of hematologic malignancies. A reproducible classification that is…