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Introduction Bile acids have long been understood to be physiologic detergent molecules synthesized from cholesterol and critical for the absorption of intestinal lipids. More recently we have come to comprehend their broader role as signaling molecules in a variety of…
Abbrevations ACOX acyl-CoA oxidase ASBT apical sodium bile acid transporter CTX cerebrotendinous xanthomatosis FAB-MS fast atom bombardment ionization mass spectrometry GC-MS gas chromatography−mass spectrometry GGT γ-glutamyltranspeptidase LDL low-density lipoprotein LSIMS liquid secondary ionization mass spectrometry PFIC progressive familial intrahepatic cholestasis…