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Key Points Infantile hemangiomas (IHs) are the most common soft tissue tumor of infancy, with a reported incidence of 4% to 5% in mature newborns and up to 23% in extremely preterm infants. There is often parental concern regarding the…
Key Points Papulopustular lesions on the palms and/or soles in the first month of life likely represent a self-limited inflammatory process such as eosinophilic pustular folliculitis or infantile acropustulosis—but scabies should be ruled out. Neonatal acne (a.k.a. cephalic pustulosis )…
Key Points Owing to their cutaneous, immunologic, and renal immaturity, newborns (especially premature neonates) are at increased risk of skin infection. As a group of potentially life-threatening but often treatable diseases, infections must always be considered in a newborn with…
Key Points Healthy full-term infant skin is well developed and serves as an effective barrier. Premature infants, especially those of very low birth weight, have an ineffective barrier that increases the risk of invasive infection, dehydration, cutaneous injury, and toxic…

Introduction Viral infections are frequently associated with cutaneous manifestations, especially in children, in whom they are the most common cause of exanthems. An exanthem is defined as a skin eruption occurring as a sign of a general disease. Viral exanthems…