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Molecular Testing for Factor V Leiden and Prothrombin Gene Mutations in Inherited Thrombophilia
Factor V Leiden Factor V Leiden (FVL) refers to the specific G-to-A transition at nucleotide 1601 (c.1601G>A) in exon 10 of the factor V gene, which results in arginine to glutamine substitution at amino acid 534 of the protein (p.Arg534Gln),…