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Introduction The effects of carbon dioxide (CO 2 ), oxygen (O 2 ), and nitric oxide (NO) on the cerebrovasculature are the most pronounced, easily demonstrated, and reproduced phenomena observed in the cerebral circulation. Studies in man and animals, using…
Introduction The adult human brain represents about 2% of total body weight, but receives nearly 15% of total resting cardiac output. Under normal conditions, the brain is highly perfused and is extremely sensitive to any change or interruption in its…