Tag Richard O. Francis MD PhD

Transfusion-associated graft-versus-host disease (TA-GVHD), a rare (1 fatality reported to FDA 2011–15) and almost universally fatal complication of blood product transfusion, is due to the cotransfusion of viable lymphocytes in cellular blood products, such as whole blood, red blood cells…

Irradiation (or pathogen inactivation) of blood products is performed to abrogate the risk of transfusion-associated graft-versus-host disease (TA-GVHD), a rare and almost universally fatal complication of blood transfusion with no successful treatment options. Irradiation results in the generation of electrons…