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Acknowledgments We thank the many current and past members of the Minna lab for their contributions to lung cancer translational research and our especially our long-term collaborator, Dr. Adi Gazdar. Also we apologize to other investigators for the omission of…
Summary of Key Points Cancer genomes are characterized by the presence of a variety of alterations including base substitutions, copy-number alterations (amplifications or deletions), and structural rearrangements (translocations or chromosomal rearrangements). Among the early methods of DNA sequencing (now known…