Tag Rajeev V. Rao

The pathogenic role of antiphospholipid antibodies (APLAs) in thrombotic events was recognized 30 years ago in a study of 65 patients with systemic lupus erythematous (SLE). The antiphospholipid syndrome (APS) is a clinical entity composed of venous or arterial thrombotic…

In 1924, Emanuel Libman and Benjamin Sacks demonstrated noninfectious, nonrheumatic verrucous endocarditis in an autopsy series of four young patients with multiple symptoms. The seminal description highlighted the constellation of polyarthritis, pericarditis, fever, and cutaneous eruptions common in these patients…