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Akt-GSK3β Pro-survival Signaling Pathway in Cerebral Ischemic Injury
Introduction The balance between apoptotic signals and survival signals determines the fate of neurons after cerebral ischemia. Unobstructed activation of caspases in pathological conditions will lead to cell death; however, activation of phosphoinositide 3-kinase (PI3K)/Akt signaling pathway may counteract the…