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Molecular and Cellular Mechanisms of Ischemia-Induced Neuronal Death
Key Points Cerebral ischemia induces neuronal death through necrosis, apoptosis, necroptosis, or ferroptosis. Calcium is a critical factor in ischemic neuronal death. Both glutamate excitotoxicity and nonexcitotoxic mechanisms trigger ischemic cell death through calcium. Oxidative stress contributes to ischemic neuronal…