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Tag Qian-Yun Zhang

Automated hematology

Abstract Background The roots of automated hematology began with manual microscopy and laborious cell counting techniques. Using the Coulter principle and advances in laboratory methodology, automated hematology is now rapid and inexpensive with the complete blood cell count (CBC) being…

B-Cell Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Monoclonal B-Cell Lymphocytosis, and B-Cell Prolymphocytic Leukemia

B-Cell Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (B-CLL/SLL) Definition of Disease B-cell chronic lymphocytic leukemia (B-CLL) is a clonal disorder of mature B lymphocytes, which are characterized by small, round nuclei; highly condensed chromatin; inconspicuous nucleoli; scant cytoplasm; and unique immunophenotype.…