Key Points 1. Clinical hemostasis reflects an integrated interplay between the coagulation system, the fibrinolytic system, platelets, and the vascular endothelium. 2. The coagulation cascade has four main components, namely the contact activation, the extrinsic, the intrinsic, and the common…
Key Points 1. While medical treatment and surveillance can be used to manage select aortic pathology, it is not uncommon for patients with aortic disease to present for surgical intervention. In the setting of certain acute aortic syndromes, surgery is…
INTRODUCTION The importance of excessive blood loss after coronary artery bypass grafting (CABG) is related to its significant association with deleterious perioperative outcomes, including all the risks of blood transfusion. Blood transfusion after CABG significantly increases mortality risk, ischemic morbidity…