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Acknowledgments Studies in the author’s laboratories were supported by NIDDK grants RO1 DK54016 (PKD), RO1 DK81858 (PKD), RO1 DK92441 (PKD), RO1 DK71596 (WAA), RO1 DK109709 (WAA) and Department of Veterans Affairs Merit Awards BX002011 (PKD), BX000152 (WAA), BX002687-01 (SS) and…