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Risk Approximately 0.001 cases per 100,000 population in USA since 1980 (<5 cases a year). Endemic in developing countries. Still common in countries where mass immunization programs are not enforced. After political changes in Eastern Europe and Central Asia at…

Risk In general population: 0.4–1.3 cases per 100,000; AIDS pts: 2–7 cases per 1000. Impact of cryptococcosis: Approximately 625,000 deaths each year worldwide. Underlying immunocompromised conditions and risk factors: AIDS, systemic lupus erythematous, prolonged treatment with corticosteroids, organ transplantation, advanced…