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Tag Phuong-Chi T. Pham

Sickle cell nephropathy

1. What is the pathophysiology of sickle cell disease (SCD)? Hemolysis, vasoocclusion, and ischemia reperfusion are the clinical hallmarks of SCD. The substitution of glutamate for valine at position 6 of the hemoglobin β-chain is the mutation defining hemoglobin S…

Renal Failure in Adults

Orthotopic liver transplantation (OLT) is a well-established definitive treatment for patients with chronic advanced cirrhosis or acute fulminant hepatic failure and a viable therapeutic option for those with primary resectable hepatic malignancies with or without cirrhosis. Over the past decade…