Tag Philippe Gaulard

Hepatosplenic T-Cell Lymphoma

Definition Hepatosplenic T-cell lymphoma (HSTL) is an aggressive subtype of extranodal lymphoma characterized by a hepatosplenic presentation without lymphadenopathy and a poor outcome. The neoplasm results from a proliferation of non-activated cytotoxic T cells, usually monomorphic and medium-sized, that exhibit…