Pigmented epithelioid melanocytoma (PEM) is a rare melanocytic neoplasm composed of pigmented epithelioid and dendritic melanocytes with large vesicular nuclei. It was first described in patients with Carney complex under the rubric of epithelioid blue nevus. Carney complex is a…
Mycosis fungoides and Sézary syndrome are two closely related conditions in which neoplastic T cells infiltrate the skin and circulate in the peripheral blood. Both conditions are neoplasms that typically have a mature helper T-cell phenotype and a propensity to…
Key Points Spitz nevi can be clinically and histopathologically distinguished from melanoma in a large majority of cases. Spitz nevi are predominantly seen in children and young adults, but recent studies have shown a broader age range than was previously…