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Summary of Key Points After more than 20 years of development and a somewhat hesitant start, microbubbles have finally come of age as a contrast agent for ultrasound. The principal requirements for an ultrasound contrast agent are that it should…

Background In the past 15–20 years, the practice of contrast-enhanced ultrasound (CEUS) has moved from a technique used in a few centres to a widely employed imaging modality that is used worldwide. This change in practice has been facilitated by…