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Fogo Selvagem (Endemic Pemphigus Foliaceus)
Introduction The term pemphigus describes a group of autoimmune vesicobullous diseases where autoantibodies are directed against the ectodomains of the desmosomic strutures of the epidermis, culminating in keratinocyte detachment (acantholysis) and intraepithelial blister formation. Autoantibodies against stratified epithelial-specific desmosomal glycoproteins…