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Introduction Identification of the molecular pathways altered in benign and malignant hepatocellular tumors has significantly increased our understanding of hepatocellular tumorigenesis. The immunohistochemical markers derived from these molecular alterations have been useful in clinical pathology practice, contributing to accurate diagnosis…

. The practice of hepatopathology requires a clear understanding of liver anatomy and physiology, as a prelude to understanding the expression of pathological processes in the liver. As an anatomical entity, the liver is deceptively simple. It is large, representing…