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In recent years, there has been an explosion of discovery about proteins that function to organize components of the signal transduction machinery with their effectors at specific subcellular locales. Many of these molecular scaffolds control the assembly, trafficking, subcellular location…
45.1 Introduction to Epithelial Cell Polarity The ability of epithelial cells in gastrointestinal (GI) track to absorb selected nutrients while secreting electrolytes, enzymes, and digestive factors depends on intracellular trafficking mechanisms that establish and maintain the polarized disruption of different…