Abbreviations ACLF acute-on-chronic liver failure ALF acute liver failure HCC hepatocellular carcinoma INR international normalized ratio LT liver transplantation MELD Model for End-Stage Liver Disease SLK simultaneous liver-kidney transplantation Introduction Cirrhosis had traditionally been classified into two stages: compensated cirrhosis…
Abbreviations AIDS acquired immunodeficiency syndrome ARPKD autosomal recessive polycystic kidney disease BRTO balloon-occluded retrograde transvenous obliteration of varices DSRS distal splenorenal shunt EMT epithelial-mesenchymal transactivation FHVP free hepatic vein pressure GAVE gastric antral vascular ectasia GVE gastric vascular ectasia HHT…
Variceal hemorrhage, hepatic encephalopathy, and ascites—the major complications of cirrhosis of the liver (see Chapters 74, 93, and 94 )—result from portal hypertension, defined as an increase in hepatic sinusoidal pressure to 6 mm Hg or greater. Portosystemic collaterals decompress…
Cirrhosis, a final pathway for a wide variety of chronic liver diseases ( Box 74.1 ), is a pathologic entity defined as diffuse hepatic fibrosis with the replacement of the normal liver architecture by nodules. The rate of progression of…