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Summary and Key Features Permanent fillers comprise mostly synthetic materials that cause collagen deposition via fibroplasia as their mechanism of action. Permanent fillers are better at facial volumizing and deep structural augmentation than at “line filling.” Silicones, polyalkylimides, polyacrylamides, polymethylmethacrylate,…

Summary and Key Features Permanent fillers are materials composed of nonabsorbable or permanent materials. These agents can provide long-lasting results but carry more potential risk. Polymethylmethacrylate and liquid injectable silicone are the only currently available permanent fillers available in the…