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Overview of the Mononuclear Phagocyte System The mononuclear phagocyte system (MPS) refers to a network of cells that share the ability to engulf (i.e., internalize) and digest large particles such as whole microbes (e.g., bacteria, fungi, and viruses) or dying…
Key Points The fetus and newborn express a distinct and evolving immune system that mediates transition from intrauterine life to the microbe- and antigen-rich world. Multiple mechanisms including regulatory T cells help ensure maternofetal immune compatibility. Newborns are highly reliant…