Nishtha Sodhi Archives - Clinical Tree

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Percutaneous Closure of Patent Foramen Ovale and Atrial Septal Defect

Key Points Although patent foramen ovale (PFO) and atrial septal defect (ASD) both involve an abnormal communication across the interatrial septum, their causes are different. PFO results from lack of fusion between the septum primum and the septum secundum, whereas…

Pathophysiology of Acute Coronary Syndromes: Plaque Rupture and Atherothrombosis

The acute coronary syndromes (unstable angina, myocardial infarction [MI], sudden cardiac death) are a major cause of morbidity and mortality in developed countries. MI alone is the major cause of death in most Western countries. The rapidly increasing prevalence in…