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Etiology Lymphangioleiomyomatosis (LAM) is a systemic disease of unknown etiology, affecting almost exclusively women. LAM is characterized by idiosyncratic smooth muscle cell proliferation (LAM cells), which leads to lung cysts, systemic lymphatic abnormalities, and abdominal tumors. The main manifestation is…

The pulmonary interstitium consists of the connective tissue fibres that support the lung. It includes the intralobular interstitium beneath the alveolar epithelium, the interlobular septa and the peribronchovascular interstitium. The term interstitial lung disease (ILD) is used to refer to…