Clinical Keys for This Chapter ▪ There are two different clinicopathologic types of endometrial cancer. Type I endometrial cancers are caused by unopposed estrogenic stimulation, are endometrioid in histologic type, and generally have a good prognosis. Type II endometrial cancers…
Clinical Keys for This Chapter ▪ Most vulvar cancers are squamous cell carcinomas, and, etiologically, there are two different types. The more common type occurs in older women and is frequently related to long-standing lichen sclerosus. The less common type…
Clinical Keys for This Chapter ▪ Cervical cancer is the major cause of death from cancer in women worldwide, but most new cases and deaths occur in developing countries where screening for cervical cancer is poorly developed. ▪ Cervical cancer…
Clinical Keys for This Chapter ▪ Chemotherapy and radiation therapy both work primarily by disrupting nuclear deoxyribonucleic acid and inhibiting cellular division. They potentially kill all rapidly dividing cells. Targeted therapies are directed towards specific signaling pathways within cancer cells,…
Clinical Keys for This Chapter ▪ Mammographic screening of asymptomatic women after the age of 40 years decreases the mortality of breast cancer. About 40% of cancers detected by mammographic screening are not clinically apparent. ▪ Hyperplasia is the most…