Tag Nancy L. Van Buren MD

Metabolic complications may occur when large volumes of blood products are transfused. The so-called lethal triad of massive transfusion, including acidosis, hypothermia, and coagulopathy will be discussed in this chapter. Other complications of massive transfusion will be reviewed, including hyperkalemia,…

Autoimmune hemolytic anemia (AIHA) refers to a group of disorders where autoantibodies are directed against red blood cell (RBC) membrane antigens resulting in shortened RBC survival (normally 100–120 days) through activation of the complement system and/or RBC removal within the…

Transfusion management of the pregnant woman and fetus requires special consideration. This chapter will address the following related issues: (1) routine prenatal and neonatal transfusion testing in relationship to maternal red blood cell (RBC) alloimmunization, (2) hemolytic disease of the…