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Introduction Since both the distal common bile duct and the main pancreatic duct converge at the level of the ampulla, ampullary tumors ( Box 42.1 ) may obstruct two organs, which may lead to early onset of symptoms. However, the…

Introduction And Classification Probably the most common problems in the diagnosis of pancreatic neoplasms are the distinction of invasive ductal adenocarcinoma from its mimics and the preoperative evaluation of cystic lesions, which are increasingly recognized. Solid, cellular pancreatic neoplasms present…

Acknowledgment We thank Drs. Kerem Ozcan and Aslihan Yavas for their contributions in the preparation of this chapter. Introduction As discussed in other chapters, gallstones and inflammatory disorders constitute the vast majority of biliary tract pathology. Neoplasms and tumor-like lesions…

Acknowledgment The authors are indebted to Dr. Hulya Sahin Ozkan, Dr. Kerem Ozcan, and Ms. Rhonda Everett for their extensive contributions in the preparation of this chapter. Neuroendocrine Cell System of the Gastrointestinal Tract Neuroendocrine cells in the gastrointestinal (GI)…

CHAPTER CONTENTS Normal gallbladder 644 Macroanatomy 644 Microanatomy 645 Immunohistochemistry 646 Embryology 646 Physiology 647 Routine specimen processing 647 Congenital anomalies 647 Gallstones 648 Epidemiology 648 Cholesterol gallstones 648 Pigmented gallstones 648 Clinical features and treatment 649 Complications 650 Hydrops…

Acknowledgment The authors thank Dr. Hulya Sahin Ozkan for her contributions in the preparation of this chapter. In the ensuing chapter, the cellular lineage markers and the application of immunohistochemistry (IHC) in the diagnosis and management of specific tumor types…