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Immunoadsorption (IA) selectively removes certain plasma proteins. IA can be specific (only removing antibody specific for single antigen) or nonspecific (removing all antibodies). Although several IA systems are available worldwide, none are currently used in the United States. This chapter…
Low-density lipoprotein (LDL) apheresis (LA) removes apo-B containing lipoprotein (LDL and lipoprotein(a) [Lp(a)]). The primary indication for LA is familial hypercholesterolemia (FH), an autosomal dominant disorder of cholesterol metabolism, resulting in elevated plasma LDL-C levels. Numerous LDL-C removal methodologies are…