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The concept of stem cell transplant was first performed in 1956 in a patient with leukemia; however, this was quickly applied to nonmalignant disorders only a decade later in a patient with severe combined immunodeficiency. In patients with nonmalignant conditions,…
Hemoglobinopathies are genetically inherited conditions that originate from the lack or malfunction of components that comprise the hemoglobin (Hb) protein. Sickle cell disease (SCD) and thalassemia are the most common forms of these conditions. SCD is caused by a well-defined…