Mike Seed Archives - Clinical Tree

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Congenital heart disease: An important cause of brain injury and dysmaturation

Key points Although there have been significant improvements in the survival of infants with congenital heart disease (CHD), they remain at high risk for neurodevelopmental impairments. Brain dysmaturation and brain injury are key brain changes contributing to adverse neurodevelopmental outcomes…

Pharmacologic Intervention in the Fetus

Introduction With the arrival of echocardiography and magnetic resonance imaging (MRI), providing the means of noninvasively detecting and monitoring anomalies occurring during pregnancy, the fetus has increasingly become the target of prenatal treatment. Nonetheless, pregnancy is a unique situation, as…

Magnetic Resonance Assessment of the Fetal Circulation in Congenital Heart Disease

Introduction The ability to accurately measure blood flow and oxygen saturations across the human late-gestation fetal circulation offered by advances in magnetic resonance imaging (MRI) has provided new insights into the impact of congenital heart disease (CHD) on the developing…