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Urticaria and angioedema affect 20% of individuals at some point in their life. Episodes of hives that last for <6 wk are considered acute, whereas those that occur on most days of the week for >6 wk are designated chronic. The distinction…
Acknowledgement Substantial material from Dr. Michael Frank’s chapter in Principles and Practice of Pediatric Infectious Diseases, fifth edition, has been used and he is therefore granted appropriate authorship. Dr. Frank was a giant in the field of complement and a…