Physical Address
304 North Cardinal St.
Dorchester Center, MA 02124
Wilson Disease and Related Disorders
Key Points 1 Wilson disease (WD) is an autosomal recessive disorder of copper metabolism caused by disease-specific defects in the ATP7B gene that encodes a copper-transporting P-type adenosine triphosphatase (ATPase) expressed primarily in the trans-Golgi network of hepatocytes. 2 Loss…