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Abstract Normal blood pressure (BP) regulation involves the integrated actions of multiple cardiovascular, renal, neural, endocrine, and local tissue control systems. Chronic hypertension is a disorder of long-term BP regulation, although short-term BP control systems may also be affected. Abnormal…

Acknowledgments The authors’ research was supported by grants from the National Heart, Lung and Blood Institute (PO1 HL51971), National Institute of General Medical Sciences (P20 GM104357), National Institute of Diabetes and Digestive and Kidney Diseases (1K08DK099415-01A1), and the American Heart…