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Acknowledgment In memory of Frank B. Diamond, Jr, MD. Disorders of calcium, magnesium, and phosphate metabolism and of bone formation, accrual, and maintenance during the first 2 decades of life result from suboptimal ingestion, absorption, or retention of constituent nutrients,…
Introduction Hormones exert their actions by binding to specific receptor proteins, a process that induces conformational changes or compartmental redistribution of these proteins. The activated receptor is now capable of inducing positive (or negative) intracellular effects that ultimately are recognized…