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Key Concepts Conjunctival limbal autograft (CLAU) represents the first surgical option for unilateral limbal stem cell deficiency, given the good long-term survival results and visual outcomes. The most important risk factors contributing to graft failure are severe dry eye, chronic…
Key Concepts Renewal of the corneal epithelium results from limbal epithelial stem cells (LESCs) located at the basal layer of epithelium found at the corneoscleral limbus. The limbal stem cell niche has a crucial impact on LESC function and regulation.…