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Introduction Patients with symptomatic severe mitral valve disease due to severe mitral annular calcification (MAC) are often elderly with multiple comorbidities and have a high risk of cardiovascular death. Their surgical risk for standard mitral valve surgery is high due…

Background The transfemoral approach remains the first-line access choice for transcatheter aortic valve replacement (TAVR). Initially up to a third of patients were unsuitable for the transfemoral approach, although this has decreased to less than 10% with contemporary valve designs.…