Human herpesvirus 8 (HHV-8) is an oncogenic virus identified in tissue specimens from patients with Kaposi sarcoma (KS). Because of this association, it is also known as Kaposi sarcoma–associated herpesvirus . HHV-8 is the etiologic agent of two additional lymphoproliferative…
Human herpesvirus 6 (HHV-6A and HHV-6B) and human herpesvirus 7 (HHV-7) cause ubiquitous infection in infancy and early childhood. HHV-6B is responsible for the majority of cases of roseola infantum ( exanthem subitum or sixth disease ) and is associated…
In 1872, Moritz Kaposi, a Hungarian dermatologist, first described in five men an aggressive, pigmented, multicentric sarcoma of the skin that disseminated to multiple sites. It was rare and received little attention until similar lesions were observed in African children…
Human Herpesvirus 6 Human herpesvirus 6 (HHV-6) was first isolated from the peripheral blood lymphocytes of adults with lymphoproliferative diseases and HIV infection and was named human B-lymphotropic virus. When additional isolates were identified in CD4 + lymphocytes, further characterization…