Tag Mark J. Arends

Neoplasia and carcinogenesis

General Characteristics of Neoplasms (Tumours) ➤ Tumours arise due to accumulation of multiple genetic alterations (e.g. mutations, deletions, translocations) and epigenetic changes (e.g. promoter methylation) in cells driving clonal evolution ➤ These changes result in abnormal (neoplastic) cell growth, forming…