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Second-line therapy in advanced non–small cell lung cancer
CLINICAL PEARLS For immunotherapy-naïve patients, second-line anti-PD-1/PD-L1 inhibitors are preferred over cytotoxic chemotherapy due to improved efficacy and tolerability. For patients with disease progression on first-line immunotherapy monotherapy, second-line cytotoxic chemotherapy with platinum doublet is appropriate. For patients with progression…