Physical Address

304 North Cardinal St.
Dorchester Center, MA 02124

Tag Mariana Castells

Drug Allergy

Definition About 80% of adverse drug reactions are predictable and dose dependent, whereas about 20% are unpredictable and dose independent ( E-Fig. 234-1 ). These latter reactions include immediate and delayed drug allergies and hypersensitivities ( Fig. 234-1 ). Epidemiology…

Anaphylaxis

Definition Anaphylaxis arises when mast cells and possibly basophils secrete potent mediators that have effects on vasculature, smooth muscle, mucous glands, and nerves, thereby eliciting a systemic response. Although mast cells in any organ system may be involved, dictated in…