Infectious Exanthems Exanthematous disorders are numerous, and commonly encountered, because they have many similarities, often a source of clinical confusion. In establishing a diagnosis, the clinician should not only attend to the basic character of the exanthem but also to…
Infection and disease develop when the host immune system fails to protect adequately against potential pathogens. In individuals with an intact immune system, infection occurs in the setting of naïveté to the microbe and absence of or inadequate preexisting microbe-specific…
Key Points Maternal transmission of Toxoplasma gondii in the first trimester causes the greatest damage to the fetus, while infections later in pregnancy are more readily transmissible to the fetus. No neonate should be discharged from a birth hospital without…
Solid-organ transplantation (SOT) is an accepted therapy for end-stage disease of many organs. As transplants are increasingly common, an expanding number of immunosuppressed children are at risk for developing infection after transplantation. This chapter will help establish a framework regarding…
The finding of even some eosinophils in human cerebrospinal fluid (CSF) raises the suspicion of certain pathologic states. Helminthic infestation of the central nervous system (CNS), particularly with the rat lungworm Angiostrongylus cantonensis, is the most common cause of eosinophilic…
Despite great progress in liver transplantation, infections remain a major cause of morbidity and mortality. Although not every infection can be anticipated, many types can be predicted, and some can even be prevented. The sources of pathogenic organisms can be…