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Before the availability of rotavirus vaccines, rotaviruses were the most common cause of severe infant and childhood gastroenteritis worldwide, responsible for 40% of all diarrheal hospitalizations and more than half a million deaths among children aged <5 years annually. To…
## Rotaviruses were the leading cause of severe dehydrating diarrhea in infants and young children throughout the world before rotavirus vaccines became available. Most children were infected by the time they reached 2 to 3 years of age. , Even…