Funding Information Supported by NIH NS20989. Introduction Anticoagulants continue to play a central role in the prevention of stroke. Unlike thrombolytics, anticoagulants do not degrade clot; rather, they prevent thrombus formation and propagation by reduction of fibrin formation. Anticoagulants act…
Introduction Arteriosclerosis is a generic term used for describing hardening and thickening of arteries. Atherosclerosis is the most common form and is responsible for several common clinical manifestations such as stroke, coronary artery diseases, peripheral arterial disease, and aortic aneurysm.…
Introduction The vascular endothelium is a simple monolayer of cells that line the capillary lumen and is optimally placed at the interface of the blood circulation and vessel wall. Once considered to be merely a “cellophane wrapper” of the vessel…