Definition Polyglandular syndromes are disorders of dysfunction and pathology of more than one endocrine gland. These disorders can be classified into neoplastic syndromes with abnormal endocrine cell proliferation and often, but not invariably, hormone hypersecretion, and autoimmune syndromes , in…
Normal Anatomy and Function The adrenal glands weigh 6 to 8 g in adults ( Fig. 208-1 ). Each contains a cortex, which makes steroid hormones, and a medulla, which produces catecholamines. Diseases of the adrenal medulla are discussed in Chapter…
Most endocrine disorders are due to either an excess or a deficiency of a hormone that is transported in the systemic circulation and therefore result in multiorgan manifestations. Since individual hormones commonly have multiple sites of action, patients rarely present…