Tag Lucia R. Wolgast MD

Introduction Antiphospholipid (aPL) antibodies are a heterogeneous family of autoantibodies that are primarily directed against plasma proteins complexed with anionic phospholipids that are found on damaged/activated cellular membranes, including endothelial cells, trophoblasts, platelets, and monocytes. The formation of autoantibodies against…

Introduction The antiphospholipid (aPL) syndrome (APS) is an autoimmune thrombophilic condition that is defined by a combination of clinical and laboratory criteria. In general terms, APS patients have developed circulating antibodies against plasma proteins that bind to phospholipids (i.e., aPL…