Leal Herlitz Archives - Clinical Tree

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Monoclonal immunoglobulin deposition disease

Introduction Monoclonal immunoglobulin deposition disease (MIDD) is characterized by the deposition of monoclonal light and/or heavy chains within glomerular, tubular, and vessel wall basement membranes. Three subtypes of MIDD have been described and they are subdivided according to the composition…

Infection-Related Glomerulonephritis

In previous editions, this chapter was titled “Post-infectious Glomerulonephritis,” which aptly describes classic post-streptococcal glomerulonephritis (PSGN) but is a misnomer for the increasingly recognized forms of glomerulonephritis (GN) that are manifestations of ongoing infection. Indeed, infection has a much broader…