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Etiology Histoplasmosis is caused by Histoplasma capsulatum, a dimorphic fungus found in the environment as a saprobe in the mycelial (mold) form and in tissues in the parasitic form as yeast. Epidemiology Two varieties of Histoplasma cause human histoplasmosis. The…
Acknowledgment The authors recognize previous contributions of Janet A. Englund and Jane L. Burns to this chapter. Sickle Hemoglobinopathy The decrease in splenic function in children with hemoglobin SS (Hb SS) disease results in increased susceptibility to fulminant bacterial infection,…